Richard Marchese Robinson
Computational Toxicology
I am a 4th year PhD student working under the supervision of Dr John Mitchell, carrying out research in the field of Computational Toxicology.
I spent four years studying Natural Sciences at the University of Cambridge; in the final year, I carried out research under the supervision of Dr Jonathan Goodman - modelling organic reactions using DFT.
The aim of my PhD will be the development of in silico techniques for the prediction of toxicological properties and, more broadly, the elucidation of the mechanisms of action of toxic substances. It is hoped that a better understanding of the causual factors pertaining to toxicity will yield greater predictive insight as well. Currently, I am looking at the development of cheminformatics techniques with potential applicability in this field. In particular, I have been working with Florian Nigsch to develop the use of the Winnow algorithm.
Computational toxicology seeks to predict the propensity of compounds to exhibit a range of toxicological endpoints. Currently, endpoints which are of particular interest to me include inhibition of the hERG ion channel and skin sensitization.
Richard Marchese Robinson's publications
- Contact Details:
email: rlm46( AT )cam.ac.uk