University of St Andrews, Chemistry dept.

ALDH2 mediates 5-nitrofuran activity in multiple species

Thu, 03th Mar 12

Congratulations to Linna on the publication of her paper in Chemistry and Biology. This work is in collaboration with Dr Liz Patton in Edinburgh and is entitled ALDH2 mediates 5-nitrofuran activity in multiple species.  

Tenovin-6

Thu, 03th Mar 12

A paper has recently been published in Cancer Cell which uses the chemical tool Tenovin-6, discovered by the Westwood, Lane and Lain groups in proof of concept anti-leukemia studies. http://www.sciencedirect.com/science/article/pii/S153561081100482X In addition, a recent study has shown that Tenovin-6 improves the effect of Imatinib against CML and in particular targeting [...]

Discovery and Optimisation of Novel Sirtuin Inhibitors

Thu, 03th Mar 12

Lisa gave a talk entitled “Discovery and Optimisation of Novel Sirtuin Inhibitors” at the COST action Epigenetics meeting in Braga, Portugal. The meeting “Epigenetics: Bench to Bedside” was held at the University of Minho from 15th-16th December 2011.

PPI-Net

Thu, 03th Mar 12

Nick recently joined the Management Team of PPI-Net, the UK-based Chemical Biology Network focused on the study and modulation of protein-protein interactions.

Chemical Biology: What is Its Role in Drug Discovery?

Thu, 03th Mar 12

Lisa Pirrie and Nick Westwood are authors of the chapter “Chemical Biology: What is Its Role in Drug Discovery?” in the recently published book, Drug Discovery and Development – Present and Future, ISBN 978-953-307-615-7, edited by Izet M. Kapetanovic.

The development of Novel Sialidase Inhibitors

Thu, 03th Mar 12

Paul gave a talk titled “The development of Novel Sialidase Inhibitors” at the 5th Biological and Medicinal Chemistry Symposium for Postgraduates on the 9th of december in Cambridge.

National Cancer Research Institute (NCRI) Cancer Conference

Thu, 03th Mar 12

Linna presented a poster on her research titled “Target identification of nitrofuran compound that induces melanocyte cell death in zebrafish” at the recent 7th National Cancer Research Institute (NCRI) Cancer conference in Liverpool.

Tour for CRUK Sponsors

Thu, 03th Mar 12

We recently took part in a tour of the department for people invloved in raising money for CRUK.  We gave them a guided tour of our new lab space and gave them a taste of the life of an academic Medicinal Chemist!



Welcome to the Westwood Research Group.

We are based in the School of Chemistry at the University of St Andrews and are part of the Biomedical Sciences Research Complex.

Our research interests include Chemical Biology and Natural Product Synthesis.