Robert Lowe
I studied for four years at the University of Warwick for my undergraduate degree, a Masters in Physics (MPhys). My final year project was a dynamics simulation on how viruses pack their DNA, for which my supervisor was Prof. Mike Allen. Before moving to Cambridge, I worked on an 8 week project looking at a Monte Carlo simulation of protein bound DNA overstretching with Stephen Whitelam.
I started my PhD in October 2008 with the project title of "Machine Learning Methods for Predicting Phospholipidosis". I will be using a variety of Machine Learning Methods but our first approach will involve using Random Forest. Phospolipidosis can be characterised by the accumulation of phospholipids in the lysosomes of many cell types. It may be induced by certain drugs of which the most commmon are cationic amphiphilic drugs[1].
You can find a link to my blog here where I will put up posts containing scripts I have found useful.
References
- Use of physicochemical calculation of pKa and CLogP to predict phospholipidosis-inducing potential, J. T. M. Ploemen, J. Kelder, T. Hafmans, H. V. De Sandt, J. V. Burgsteden, P. J. M. Salemink, and E. V. Esch, Exp Toxic Pathol 2004; 55: 347 - 355
- Contact Information:
- Tel: +44 (0) 1223 763078
email: ral64( AT )cam.ac.uk